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inhibitors such as adalimumab (Humira) and etanercept (Enbrel), and interleukin-17 (IL-17) inhibitors such as secukinumab (Cosentyx) and ixekizumab (Taltz). These and other biologics have been found to improve mobility and possibly fight the progression of AS (you can read more about them in Chapter 8).

      

Though AS has no cure, most who have the disease suffer from mild to moderate symptoms and do fairly well. Physical therapy can be very helpful in preserving spinal strength and flexibility. More extreme cases of AS may require surgical replacement of one or more joints, but spinal surgery is rarely indicated as the spines of AS patients are so fragile.

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