Copyright

      Thorsons

      An imprint of HarperCollinsPublishers

      1 London Bridge Street

      London SE1 9GF

       www.harpercollins.co.uk

      First published by Atria Books, an imprint of Simon & Schuster, Inc.

      This UK edition published by Thorsons 2019

      FIRST EDITION

      © David Sinclair PhD 2019

      Cover layout design © HarperCollinsPublishers Ltd 2019

      Cover illustration © MGB Watercolor Art 2019

      Illustrations and Sinclairfont by Catherine L. Delphia

      Illustrations in Cast of Characters by David Sinclair

      Thanks to Christine Liu and her team at the Innovative Genomics Institute (IGI) for permission to use the Glossary icons. Thanks to Wikipedia for biographical facts in the cast of characters.

      A catalogue record of this book is available from the British Library

      David Sinclair PhD asserts the moral right to be identified as the author of this work

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      Source ISBN: 9780008353742

      Ebook Edition © October 2019 ISBN: 9780008292362

      Version 2019-10-29

      Information about External Hyperlinks in this ebook

      Please note that footnotes and endnotes in this ebook may contain hyperlinks to external websites as part of bibliographic citations. These hyperlinks have not been activated by the publisher, who cannot verify the accuracy of these links beyond the date of publication.

       Contents

       Cover

       Title Page

       Copyright

       Dedication

       Introduction: A Grandmother’s Prayer

       PART I: WHAT WE KNOW (THE PAST)

       1. Viva Primordium

       2. The Demented Pianist

       3. The Blind Epidemic

       PART II: WHAT WE’RE LEARNING (THE PRESENT)

       4. Longevity Now

       5. A Better Pill to Swallow

       6. Big Steps Ahead

       7. The Age of Innovation

       PART III: WHERE WE’RE GOING (THE FUTURE)

       8. The Shape of Things to Come

       9. A Path Forward

       Conclusion

       Acknowledgments

       Notes

       Sinclair Disclosure

       The Scale of Things

       Cast of Characters

       Glossary

       List of Searchable Terms

       Praise for Lifespan

       About the Authors

       About the Publisher