Principles of Virology. Jane Flint
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some animal viruses
2 Chapter 3Table 3.1 Some viral vectors
3 Chapter 4Table 4.1 Functions of virion proteinsTable 4.2 Nomenclature used in description of virus structureTable 4.3 Some virion enzymes
4 Chapter 7Table 7.1 Strategies of transcription of viral DNA templatesTable 7.2 Eukaryotic RNA polymerases synthesize different classes of cellular an...Table 7.3 Properties and functions of some viral transcriptional regulatorsTable 7.4 Viral RNA polymerase III transcription units
5 Chapter 9Table 9.1 Viral origin recognition proteinsTable 9.2 Replication systems of large DNA virusesTable 9.3 Viral enzymes of nucleic acid metabolism
6 Chapter 10Table 10.1 Comparison of retroviral integration site preferences in human cellsTable 10.2 Comparison of retroviral and hepadnaviral reverse transcription
7 Chapter 12Table 12.1 Some viral envelope glycoprotein precursors processed by secretory pa...
8 Chapter 13Table 13.1 Common sequence motifs required for budding of enveloped virus partic...
9 Chapter 17Table 3.1 Some viral modulators of the interferon responseTable 3.2 Some chemokine receptors and their ligands
10 Chapter 19Table 5.1 Incubation periods of some common virusesTable 5.2 Some persistent viral infections of humansTable 5.3 Epstein-Barr latency programs
11 Chapter 20Table 6.1 Oncogenic viruses and cancerTable 6.2 Some transforming gene products of adenoviruses, papillomaviruses,...
12 Chapter 21Table 7.1 Viral vaccines licensed in the United StatesTable 7.2 When can we expect an HIV vaccine?
13 Chapter 22Table 8.1 Approved drugs targeted against human immunodeficiency virus
14 Chapter 24Table 10.1 Fitness decline compared to initial virus clone after passage thr...
15 Chapter 27Table 13.1 Viroids and satellitesTable 13.2 Some transmissible spongiform encephalopathies
List of Illustrations
1 Chapter 1Figure 1.1 The human virome. Our knowledge of the diversity of viruses that ca...Figure 1.2 Tracking ancient human migrations by the viruses they carried. The ...Figure 1.3 References to viral diseases from the ancient literature. (A) An im...Figure 1.4 Three Broken Tulips . A painting by Nicolas Robert (1624–1685), now ...Figure 1.5 Characteristic smallpox lesions in a young victim. Illustrations li...Figure 1.6 Pasteur’s famous swan-neck flasks provided passive exclusion of micro...Figure 1.7 The pace of discovery of new infectious agents in the dawn of virolog...Figure 1.8 Filter systems used to characterize/purify virus particles. (A) The...Figure 1.9 Electron micrographs of virus particles following negative staining. ...Figure 1.10 Size matters. (A) Sizes of animal and plant cells, bacteria, virus...Figure 1.11 Lesions induced by tobacco mosaic virus on an infected tobacco leaf....Figure 1.12 The Baltimore classification. The Baltimore classification assigns...Figure 1.13 Viral families sorted according to the nature of the viral genomes. ...Figure 1.14 Landmarks in the study of viruses. Key discoveries and technical a...
2 Chapter 2Figure 2.1 The viral infectious cycle. The infectious cycle of poliovirus is s...Figure 2.2 Different types of cell culture used in virology. Confluent cell mo...Figure 2.3 Production of organoids from stem cells. The different germ layers ...Figure 2.4 Production of airway-liquid interface cultures of bronchial epithel...Figure 2.5 Development of cytopathic effect. (A) Cell rounding and lysis durin...Figure 2.6 Growth of viruses in embryonated eggs. The cutaway view of an embry...Figure 2.7 Plaques formed by different animal viruses. (A) Photomicrograph of ...Figure 2.8 The dose-response curve of the plaque assay. The number of plaques ...Figure 2.9 Transformation assay. Chicken cells transformed by two different st...Figure 2.10 Hemagglutination assay. (Top) Samples of different influenza virus...Figure 2.11 Polysome analysis. To study the association of mRNAs with ribosome...Figure 2.12 Direct and indirect methods for antigen detection. (A) The sample ...Figure 2.13 Detection of viral antigen or antibodies against viruses by enzyme...Figure 2.14 Lateral flow immunochromatographic assay. A slide or “dipstick” co...Figure 2.15 Using fluorescent proteins to study virus particles and virus-infe...Figure 2.16 Polymerase chain reaction. The DNA to be amplified is mixed with n...Figure 2.17 Workflow for VS-Virome. Shown is the computational pipeline design...Figure 2.18 Comparison of bacterial and viral reproduction. (A) Growth curve f...Figure 2.19 One-step growth curves of animal viruses. (A) Growth of a nonenvel...Figure 2.20 Chromatin immunoprecipitation and DNA sequencing, ChiP-seq. This t...Figure 2.21 Interactions between human proteins and Nipah virus proteins. Netw...Figure 2.22 Single-cell virology. (A) A microfluidic device with 6,400 wells i...
3 Chapter 3Figure 3.1 The Baltimore classification. All viruses must produce mRNA that ca...Figure 3.2 Structure and expression of viral double-stranded DNA genomes. (A) ...Figure 3.3 Structure and expression of viral gapped, circular, double-stranded