Physiology of Human Reproduction. George Osol

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Physiology of Human Reproduction - George Osol


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      Notes for Students

      George Osol, PhD

       Professor Emeritus

       Department of Obstetrics, Gynecology and Reproductive Sciences

       University of Vermont Larner College of Medicine

       Burlington, VT, USA

      This edition first published 2021

      © 2021 John Wiley & Sons Ltd

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      The right of George Osol to be identified as the author of this work has been asserted in accordance with law.

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       Library of Congress Cataloging‐in‐Publication Data

      Names: Osol, George, author.

      Title: Physiology of human reproduction : notes for students / George Osol.

      Description: Hoboken, NJ : Wiley‐Blackwell, 2021. | Includes index.

      Identifiers: LCCN 2020026467 (print) | LCCN 2020026468 (ebook) | ISBN 9781119609582 (paperback) | ISBN 9781119609605 (Adobe PDF) | ISBN 9781119609575 (epub)

      Subjects: MESH: Reproduction–physiology | Study Guide

      Classification: LCC QP251 (print) | LCC QP251 (ebook) | NLM WQ 200.1 | DDC 612.6–dc23

      LC record available at https://lccn.loc.gov/2020026467 LC ebook record available at https://lccn.loc.gov/2020026468

      Cover Design: Wiley

      Cover Image: © Chad Baker/Getty Images

      I would like to thank Wiley, particularly James Watson, Anne Hunt, and D. Vincent Rajan for their editorial assistance and guidance with the publication and copyediting process, and my family for their patience and support.

      Chapter 1: The Adult Male

      1 1. Three basic requirements for male fertility

      2 2. GnRH

      3 3. LH and FSH

      4 4. Pulsatile release

      5 5. First vs. second messengers

      6 6. Leydig cells

      7 7. Action of LH

      8 8. Testosterone

      9 9. Sertoli cells

      10 10. Three main types of sex steroids

      11 11. Aromatization

      12 12. Conversion of testosterone into estrogen

      13 13. Action of FSH

      14 14. Inhibin

      15 15. Sertoli cell functions

      16 16. The blood-testis barrier

      17 17. Spatial relationships in males vs. females

      18 18. Diverse actions of testosterone

      19 19. Actions of testosterone in utero

      20 20. Sexual differentiation

      21 21. Androgens during puberty

      22 22. DHT

      23 23. 5α-reductase

      24 24. Androgen insensitivity syndrome (AIS)

      25 25. Sperm count

      26 26. Seminiferous tubules

      27 27. Spermatogonia

      28 28. Primary spermatocytes

      29 29. Secondary spermatocytes

      30 30. Alignment of maternal and paternal chromosomes; genetic diversity

      31 31. Spermatids

      32 32. Acrosome

      33 33. Axoneme

      34 34. Spermiogenesis

      35 35. Gymnosperm (X) vs. androsperm (Y)

      36 36.


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