Oral Biofilms. Группа авторов

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Oral Biofilms - Группа авторов


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The gastrointestinal tract is highly colonized by different microorganisms. Within the mucous layer, the close contact enables biofilm formation. Also, the ability of Clostridium difficile to form biofilms hinders treatment with antibiotics [19].

      Antibiofilm Therapy

      The biofilm matrix serves as a barrier not only to antimicrobial agents but also to immune cells. Even if phagocytes can penetrate they are ineffective, and the release of intracellular compounds increases the density and integrity of the biofilm matrix [3]. In biofilms, bacteria may become more virulent through the exchange of genes, including resistance genes [3]. Most importantly, there are subpopulations of dormant bacteria with metabolically low activity that are non-subdividing and, following resistance against antimicrobials, require metabolically active cells [3].

      Oral Biofilms

      Dental Biofilm Formation


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