“Put it down! Down, this instant, Watson — this instant, I say!” His head sank back upon the pillow and he gave a deep sigh of relief as I replaced the box upon the mantelpiece. “I hate to have my things touched, Watson. You know that I hate it. You fidget me beyond endurance. You, a doctor — you are enough to drive a patient into an asylum. Sit down, man, and let me have my rest!”

      The incident left a most unpleasant impression upon my mind. The violent and causeless excitement, followed by this brutality of speech, so far removed from his usual suavity, showed me how deep was the disorganization of his mind. Of all ruins, that of a noble mind is the most deplorable. I sat in silent dejection until the stipulated time had passed. He seemed to have been watching the clock as well as I, for it was hardly six before he began to talk with the same feverish animation as before.

      “Now, Watson,” said he. “Have you any change in your pocket?”

      “Yes.”

      “Any silver?”

      “A good deal.”

      “How many half-crowns?”

      “I have five.”

      “Ah, too few! Too few! How very unfortunate, Watson! However, such as they are you can put them in your watch-pocket. And all the rest of your money in your left trouser-pocket. Thank you. It will balance you so much better like that.”

      This was raving insanity. He shuddered, and again made a sound between a cough and a sob.

      “You will now light the gas, Watson, but you will be very careful that not for one instant shall it be more than half on. I implore you to be careful, Watson. Thank you, that is excellent. No, you need not draw the blind. Now you will have the kindness to place some letters and papers upon this table within my reach. Thank you. Now some of that litter from the mantelpiece. Excellent, Watson! There is a sugar-tongs there. Kindly raise that small ivory box with its assistance. Place it here among the papers. Good! You can now go and fetch Mr. Culverton Smith, of 13 Lower Burke Street.”

      To tell the truth, my desire to fetch a doctor had somewhat weakened, for poor Holmes was so obviously delirious that it seemed dangerous to leave him. However, he was as eager now to consult the person named as he had been obstinate in refusing.

      “I never heard the name,” said I.

      “Possibly not, my good Watson. It may surprise you to know that the man upon earth who is best versed in this disease is not a medical man, but a planter. Mr. Culverton Smith is a well-known resident of Sumatra, now visiting London. An outbreak of the disease upon his plantation, which was distant from medical aid, caused him to study it himself, with some rather far-reaching consequences. He is a very methodical person, and I did not desire you to start before six, because I was well aware that you would not find him in his study. If you could persuade him to come here and give us the benefit of his unique experience of this disease, the investigation of which has been his dearest hobby, I cannot doubt that he could help me.”

      I give Holmes’s remarks as a consecutive whole and will not attempt to indicate how they were interrupted by gaspings for breath and those clutchings of his hands which indicated the pain from which he was suffering. His appearance had changed for the worse during the few hours that I had been with him. Those hectic spots were more pronounced, the eyes shone more brightly out of darker hollows, and a cold sweat glimmered upon his brow. He still retained, however, the jaunty gallantry of his speech. To the last gasp he would always be the master.

      “You will tell him exactly how you have left me,” said he. “You will convey the very impression which is in your own mind — a dying man — a dying and delirious man. Indeed, I cannot think why the whole bed of the ocean is not one solid mass of oysters, so prolific the creatures seem. Ah, I am wandering! Strange how the brain controls the brain! What was I saying, Watson?”

      “My directions for Mr. Culverton Smith.”

      “Ah, yes, I remember. My life depends upon it. Plead with him, Watson. There is no good feeling between us. His nephew, Watson — I had suspicions of foul play and I allowed him to see it. The boy died horribly. He has a grudge against me. You will soften him, Watson. Beg him, pray him, get him here by any means. He can save me — only he!”

      “I will bring him in a cab, if I have to carry him down to it.”

      “You will do nothing of the sort. You will persuade him to come. And then you will return in front of him. Make any excuse so as not to come with him. Don’t forget, Watson. You won’t fail me. You never did fail me. No doubt there are natural enemies which limit the increase of the creatures. You and I, Watson, we have done our part. Shall the world, then, be overrun by oysters? No, no; horrible! You’ll convey all that is in your mind.”

      I left him full of the image of this magnificent intellect babbling like a foolish child. He had handed me the key, and with a happy thought I took it with me lest he should lock himself in. Mrs. Hudson was waiting, trembling and weeping, in the passage. Behind me as I passed from the flat I heard Holmes’s high, thin voice in some delirious chant. Below, as I stood whistling for a cab, a man came on me through the fog.

      “How is Mr. Holmes, sir?” he asked.

      It was an old acquaintance, Inspector Morton, of Scotland Yard, dressed in unofficial tweeds.

      “He is very ill,” I answered.

      He looked at me in a most singular fashion. Had it not been too fiendish, I could have imagined that the gleam of the fanlight showed exultation in his face.

      “I heard some rumour of it,” said he.

      The cab had driven up, and I left him.

      Lower Burke Street proved to be a line of fine houses lying in the vague borderland between Notting Hill and Kensington. The particular one at which my cabman pulled up had an air of smug and demure respectability in its old-fashioned iron railings, its massive folding-door, and its shining brasswork. All was in keeping with a solemn butler who appeared framed in the pink radiance of a tinted electric light behind him.

      “Yes, Mr. Culverton Smith is in. Dr. Watson! Very good, sir, I will take up your card.”

      My humble name and title did not appear to impress Mr. Culverton Smith. Through the half-open door I heard a high, petulant, penetrating voice.

      “Who is this person? What does he want? Dear me, Staples, how often have I said that I am not to be disturbed in my hours of study?”

      There came a gentle flow of soothing explanation from the butler.

      “Well, I won’t see him, Staples. I can’t have my work interrupted like this. I am not at home. Say so. Tell him to come in the morning if he really must see me.”

      Again the gentle murmur.

      “Well, well, give him that message. He can come in the morning, or he can stay away. My work must not be hindered.”

      I thought of Holmes tossing